Read what’s in the news about Astera Cancer Care and new and developing topics covering radiation treatment for cancer and related subjects.
Paper publication in Lancet Oncology:
Cabozantinib in combination with atezolizumab in patients with metastatic castration-resistant prostate cancer: results from an expansion cohort of a multicentre, open-label, phase 1b trial (COSMIC-021)
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(22)00278-9/fulltext
Lisocabtagene maraleucel as second-line therapy in adults with relapsed or refractory large B-cell lymphoma who were not intended for haematopoietic stem cell transplantation (PILOT): an open-label, phase 2 study
https://pubmed.ncbi.nlm.nih.gov/35839786/
Abstract presentation from AMSOC: Cabozantinib plus atezolizumab in advanced head and neck cancer previously treated with platinum-containing chemotherapy: Results from cohort 17 of the COSMIC-021 study
https://jitc.bmj.com/content/10/Suppl_2/A597
Recent abstract presentation from ESMO Congress – 481P – A phase I first-inhuman study of XL092 in patients with locally advanced or metastatic solid tumors: Results from dose-escalation of XL092 along and in combination with atezeolizumab.
Recent abstract presentation from ASCO Annual Meeting:
[68Ga]Ga-PSMA-11 PET baseline imaging as a prognostic tool for clinical outcomes to [177Lu]Lu-PSMA-617 in patients with mCRPC: A VISION substudy. https://ascopubs.org/doi/abs/10.1200/JCO.2022.40.16_suppl.5002
Cabozantinib (C) plus atezolizumab (A) or C alone in patients (pts) with advanced non–small cell lung cancer (aNSCLC) previously treated with an immune checkpoint inhibitor (ICI): Results from Cohorts 7 and 20 of the COSMIC-021 study.
https://ascopubs.org/doi/abs/10.1200/JCO.2022.40.16_suppl.9005
Evolution of biomarker testing in advanced non-small cell lung cancer (aNSCLC) and metastatic breast cancer (mBC) in U.S. community practices.
https://ascopubs.org/doi/abs/10.1200/JCO.2022.40.16_suppl.e18778
Phase 2/3, randomized, open-label study of an individualized neoantigen vaccine (self-amplifying mRNA and adenoviral vectors) plus immune checkpoint blockade as maintenance for patients with newly diagnosed metastatic colorectal cancer (GRANITE).
https://ascopubs.org/doi/abs/10.1200/JCO.2022.40.16_suppl.TPS3635
Lisocabtagene maraleucel (liso-cel) as second-line (2L) therapy for R/R large B-cell lymphoma (LBCL) in patients (pt) not intended for hematopoietic stem cell transplantation (HSCT): Primary analysis from the phase 2 PILOT study.
https://ascopubs.org/doi/abs/10.1200/JCO.2022.40.16_suppl.7062
Recent abstract presentation from ASCO GU: A phase Ib, open-label study evaluating the safety and efficacy of ipatasertib + rucaparib in patients with metastatic castration-resistant prostate cancer (mCRPC).
https://ascopubs.org/doi/abs/10.1200/JCO.2022.40.6_suppl.095
Recent abstract presentation from ASCO Quality Care: Evaluating the effect of a scalable cancer-navigation program on total cost of care.
https://ascopubs.org/doi/abs/10.1200/JCO.2022.40.28_suppl.004
Recent abstract presentation from ASTRO: A Phase 2 Study of Magrolimab Combination Therapy in Patients with Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma
https://www.redjournal.org/article/S0360-3016(21)03344-7/fulltext